Focusing on how the international agenda, national strategies, and country-specific programs can foster child well-being draws attention to resources and challenges at multiple levels and in multiple domains. This review focused on physical health, behavioral adjustment, psychological well-being, social relationships, safety, cognitive well-being, and economic security in the Gulf countries as a way to take a holistic approach to child well-being that is best fostered through a multisectoral approach with different government and non-governmental organizations working together. Enforcement of existing policies as well as monitoring and evaluation to ensure that policies and programs are having their intended effects are an important part of efforts to promote child well-being. Recommendations are provided to promote child well-being in seven domains: (1) physical health (e.g., increase breastfeeding; promote healthy eating and exercise to address obesity); (2) behavioral adjustment (e.g., treat drug use as a public health rather than criminal matter to remove barriers to prevention and treatment); (3) psychological well-being (e.g., prioritize mental health as much as physical health); (4) social relationships with parents, peers, and non-family adults (e.g., implement anti-bullying programs; (5) safety (e.g., train professionals in how to respond to reports of abuse, outlaw corporal punishment); (6) cognitive well-being (e.g., promote school readiness through early childhood education, reform education systems to build skills for a knowledge economy); (7) economic security (e.g., ensure social safety nets of government benefits).