Using a cluster-randomized controlled trial design, this study examined the comparative effectiveness of Dating Matters comprehensive prevention model (DM) compared to a standard-of-care (SC) teen dating violence program (Safe Dates) in 46 schools across 4 urban U.S. sites. Ten to twelve middle schools per site were randomized to implement either DM or SC. Data were/are being collected from 5 cohorts of students, starting in 6th grade through high school. Students completed self-report surveys twice per year while in middle school and once per year in high school. Papers in this symposium will present the middle school trial results on various outcomes for Cohorts 3 and 4, who started 6th grade in either Year 1 (2012-13) or Year 2 (2013-14) of implementation, as students in the DM condition in these cohorts had the potential for full exposure to all 3 years of DM components. High school data for this sample are still being collected. The total student sample for these two cohorts is 3,301; each paper abstract lists the particular sample used for that study. All analyses are intent-to-treat. We used a structural equation modeling framework with multiple imputation to account for missing data to assess the equivalence of outcomes on a variety of outcomes presented in the three papers in this symposium, including but not limited to TDV, other relationship behaviors, bullying, substance use, delinquency, sexual violence, and sexual risk behaviors.