Methods: Observational study design using a retrospective population-based cohort of women in Pennsylvania who gave birth between 2006 and 2012 and smoked during the first trimester of pregnancy. Community-level penetration of home visiting services was calculated as the proportion of prenatally enrolled clients served within a given year in a given county to welfare-enrolled women within that county with a birth in the same year, and was categorized into quartiles for analysis. The main outcome measure was smoking cessation in the third trimester as reported on the birth certificate. Multivariable logistic regression analysis examined the association of county-level penetration of home visiting with prenatal smoking cessation, adjusted for temporal trends, socio-demographic factors, and urbanicity, and accommodating the correlation due to clustering of women within counties.
Results: An annual average of 25,000 women in 67 counties were included for analysis. County-level annual penetration ranged from 0.0% to 27.3%, with quartiles of <0.1%, 0.1-1.4%, 1.4-5.5%, and 5.5-27.3%. The adjusted odds of prenatal smoking cessation were significantly increased for women in counties with the highest penetration of home visiting (>5.5%) compared to those with the lowest levels (<0.1%) (OR=1.24; 95% CI: 1.04, 1.47; p=0.015); the predicted probability of prenatal smoking cessation was 21.1% and 17.9%, respectively. In a sensitivity analysis adjusting for individual-level program enrollment, the effect of county-level penetration remained stable and statistically significant.
Conclusions: County-level penetration of home visiting services is a significant predictor of prenatal smoking cessation, independent of program participation. Service penetration within a community may be an important consideration of scale-up efforts, as increased reach may afford benefits beyond program participants. The mechanisms driving the effect of penetration within communities require further study but may include diffusion of norms or a robust service infrastructure.