Participants included 144 children (ages 6 – 11; 53% African American) with ODD (n = 115) or CD (n = 29) randomly assigned to treatment in the community (COMM; n = 72) or clinic (CLINIC; n = 72). Variables across child, parent, and family domains were examined in relation to changes in child externalizing behaviors or number of ODD and CD symptoms endorsed at pretreatment, posttreatment, and 36-month follow-up. Associations between treatment parameters (e.g., hours of child, parent, and parent-child treatment received, treatment completion, referral for additional services) and child outcomes were also explored. Four significant moderators were found. Higher baseline child impairment among those in COMM was associated with higher posttreatment symptoms whereas in CLINIC, baseline impairment was not differentially related to outcomes. In addition, those with no ADHD diagnosis in COMM had lower DBD symptoms at posttreatment whereas those with no ADHD diagnosis in CLINIC had higher symptoms. At 36-month follow-up, those with lower baseline family conflict in COMM had higher externalizing behavior whereas those with lower baseline family conflict in CLINIC had lower externalizing behavior. Several predictors were also found: children who had no history of interpersonal violence and whose parents had lower depressive symptoms, higher incomes, and were employed had lower posttreatment symptoms. Response was also related to a few treatment parameters (e.g., hours of child and parent treatment, treatment completion, referral for services). We discuss implications of these findings for maximizing the benefits of modular treatment by personalizing approaches for children with DBD.